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Pediatric acute kidney injury

Pediatric acute kidney (renal failure) injury refers to the sudden loss of kidney function due to an underlying illness.

Overview

What is a pediatric acute kidney injury?

Acute (sudden) kidney injury, formerly called acute renal failure, occurs when a kidney is damaged suddenly due to an illness or condition – not because of a blow or injury to a kidney as the name might suggest. It’s a sudden onset of kidney failure that can happen within a few hours or days.

Signs and Symptoms

What are the signs and symptoms of a pediatric acute kidney injury?

Causes

What are the causes of a pediatric acute kidney injury?

Slow blood flow caused by:

  • Blood or fluid loss

  • Burns

  • Heart attack or heart failure

  • Low blood pressure

  • Major surgery

  • Organ failure

  • Overuse of NSAID pain medicines (ibuprofen, ketoprofen, naproxen)

  • Severe allergic reactions

Conditions:

  • Certain kidney diseases or conditions, including hemolytic uremic syndrome

  • Multiple myeloma cancer (cancerous plasma cells)

  • Scleroderma (diseases that affect connective tissues that support internal organs)

  • Sepsis (life-threatening infection)

  • Inflamed blood vessels, or "vasculitis", which can scar blood vessels, making them stiff, weak and narrow

Blockage of the urinary tract caused by:

  • Blood clots in the urinary tract

  • Cancer

  • Kidney stones

  • Nervous system problems that affect the bladder